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KMID : 1147820180070020070
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Journal of Naturopathy
2018 Volume.7 No. 2 p.70 ~ p.74
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Antioxidant and Anti-aging Activities of Ethanol Extracts from Defatted Perilla frutescens
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Kang Hyun
Lee Sung-Gyu
Song Gap-Jung
Chung Moon-Suk
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Abstract
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Purpose: This study was conducted to investigate the antioxidative, collagenase and elastase activities of defatted perilla ethanol extracts. In addition, the possibility of its use as a functional cosmetic material has been studied.
Methods: In order to investigate the antioxidant function of the perilla extract, electron spin resonance (ESR) was measured with a spectrometer by analyzing the scavenging ability of diphenyl-β-picrylhydrazyl (DPPH) free radicals.
Results: The antioxidant activity of DPPH free radical scavenging activity of the perilla extract was about 68% at 85 μg/ml, 85% at 20 μg/ml, 90% at 40-100 μg/ml, and showed antioxidant ability. The inhibitory activity of collagenase was increased to 4.1% at 20 mg/ml, 12% at 40 mg/ml and 26.7% at 100 mg/ml. The inhibitory activity increased in proportion to the concentration. The inhibitory activity of elastase was increased to 3.8% at 20 mg/ml, 15% at 40 mg/ml, 28% at 80 mg/ml and 35.7% at 100 mg/ml.
Conclusions: These results suggest that the ethanol extract of perilla may inhibit the antioxidant activity and the activity of collagenase and elastase to improve the skin aging and wrinkles.
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KEYWORD
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Defatted perilla, Antioxidant, Anti-oxidative, DPPH, Collagenase
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